William Buick celebrated a long-awaited Breeders' Cup winner when Wuheida struck in the Filly & Mare Turf at Del Mar for Charlie Appleby.
Buick had his mount handy in third going into the first turn and got a great response from the Godolphin-owned three-year-old in the straight.
In contrast, Frankie Dettori found himself looking for room on the strong-travelling Queen's Trust as Sir Michael Stoute's four-year-old made her bid to repeat last year's success.
She finished with a real rattle but all too late, and it was the Aidan O'Brien-trained Rhododendron under Ryan Moore who proved the main threat to the winner. Cambodia was third.
Buick - who was left in tears when The Fugue was caught close home by Moore and Magician in the 2013 running of the Turf and missed a large part of this summer when injured in the fatal fall of Permian in America in August - said: "I can't explain it, it means everything to me.
"I've had plenty of goes and not been successful, so it means everything. My feelings are ones of joy, as it is always tough coming here into the back yard of the Americans, and although I have been to a few Breeders' Cups it is my first winner at one.
"It's a big team effort - a big thank you to everyone at home."
He added: "She's just a push-button ride and I knew I could send her forward from the gate, while the trip was always going to suit her and I had plenty of horse underneath me when I turned in.
"Charlie targeted this race for her from a long way out. He is a great trainer and gives me lots of confidence."
Appleby said: "I knew I had the filly in good order, and she has pleased me through the week. Running to the first turn I knew she was in the right position and William gave her a peach of a ride.
"Travelling well is in my view the key when you come out here and in that respect everything went to plan, while I thought her work on Tuesday was very pleasing."
Appleby said he was hopeful the daughter of Dubawi, who also won a Group One as a two-year-old, would stay in training next year.
He said: "It's great for my team, who have worked so hard, and His Highness (Sheikh Mohammed) for letting me bring her here.
"Going forward I'm very hopeful she will be around. It's funny, Sir Michael Stoute watched her on the track the other day and commented on what a very good four-year-old she could be.
"Obviously she is a very valuable filly now and we will talk to Sheikh Mohammed about that."
O'Brien refused to blame Rhododendron's draw in stall 14 for defeat, saying: "No, there wasn't an advantage. She's run very well and I'm delighted with that. There are no excuses."
The race was run over a furlong shorter than 12 months ago and Stoute said of fifth-placed Queen's Trust: "She's run really well and was flying at the death, but we always knew the step back in distance would be a problem."